Healthy Diet May Counteract Heart Disease Gene

TUESDAY, Oct. 11 (HealthDay News) -- A healthy diet with lots of fruits and vegetables can significantly weaken a effect of a gene associated with an increased risk of heart disease, a new study suggests.In a study, published in a current online edition of a journal PLoS Medicine, researchers carefully thought about a link between a 9p21 gene variant and diet in more than 27,000 people of five ethnicities -- Arab, European, Chinese, Latin American and South Asian.The findings showed that a risk of heart attack in people with a 9p21 gene variant who ate a healthy diet composed mainly of raw vegetables, fruits and berries was similar to that of people without a high-risk gene variant.The international study was led by researchers at McMaster and McGill universities in Canada."We observed that a effect of a high-risk genotype can be mitigated by consuming a diet high in fruits and vegetables," joint principal investigator Sonia Anand, a researcher at a Population Health Research Institute and a professor of medicine and epidemiology at McMaster's School of Medicine, said in a McMaster University news release. "Our results support a public health recommendation to consume more than five servings of fruits or vegetables as a way to promote good health.""Our investigate suggests there may be an important interplay between genes and diet in cardiovascular disease," added lead author Ron Do, who is now at a Center for Human Genetics Research at Massachusetts General Hospital but conducted a investigate as part of his doctoral program at McGill. "Future investigate is necessary to understand a mechanism of this interaction, which will shed light on a underlying metabolic processes that a 9p21 gene is involved in."More informationThe U.S. Food and Drug Administration outlines how to eat for a healthy heart.


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