Fried scorpion is a traditional dish from Shangdong, China.
As a part of Chinese medicine, scorpion wine and snake wine are used as analgesic and antidote.
One of earliest occurrences of the scorpion in culture is its inclusion, as Scorpio, in the twelve signs of the series of constellations known as the Zodiac by Babylonian astronomers during the Chaldean period.:462
In North Africa and South Asia, the scorpion is a significant animal culturally which appears as a motif in art, especially in Islamic art in the Middle East. It is perceived both as an embodiment of evil as well as a protective force which counters evil, such as a dervish's powers to combat evil. In another context, the scorpion portrays human sexuality.Scorpions are used in folk medicine in South Asia especially in antidotes for scorpion stings.
In ancient Egypt the goddess Serket was often depicted as a scorpion, one of several goddesses who protected the Pharaoh.
Surrealist filmmaker Luis Buñuel makes notable symbolic use of scorpions in his 1930 classic L'Age d'or (The Golden Age).The first two pages of Ian Fleming's novel Diamonds Are Forever are told from the point of view of an African scorpion which kills and eats a beetle and is then casually crushed and killed itself, by one of the villains whom James Bond would later confront and eventually crush.
The key ingredient of the venom is a scorpion toxin protein.
Short chain scorpion toxins constitute the largest group of potassium (K+) channel blocking peptides; an important physiological role of the KCNA3 channel, also known as KV1.3, is to help maintain large electrical gradients for the sustained transport of ions such as Ca2+ that controls T lymphocyte (T cell) proliferation. Thus KV1.3 blockers could be potential immunosuppressants for the treatment of autoimmune disorders (such as rheumatoid arthritis, inflammatory bowel disease and multiple sclerosis).The venom of Uroplectes lineatus is clinically important in dermatology.
Toxins being investigated include:
Chlorotoxin is a 36-amino acid peptide found in the venom of the deathstalker scorpion (Leiurus quinquestriatus) which blocks small-conductance chloride channels. The fact that chlorotoxin binds preferentially to glioma cells has allowed the development of new methods, that still are under investigation, for the treatment and diagnosis of several types of cancer.
Maurotoxin from the venom of the Tunisian Scorpio maurus palmatus